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  • Predictors of melanoma prognosis

Predictors of melanoma prognosis

A series of three publications reported studies investigating the prognosis associated with melanomas. 

These three studies were:

  • A retrospective study using the VMS database examined the influence of various primary tumour characteristics in advanced metastatic melanoma
  • Prospective cohort study looked at the role of BRAF mutations
  • Prospective study using the VMS database examined prognosis for patients with cutaneous (skin) metastases

The retrospective study looking at the influence of various primary tumour characteristics in patients diagnosed with stage IV melanoma between 2003 and 2012, who had a median follow-up of five years, found that primary tumour thickness was the most significant prognostic factor in stage IV melanoma.

In the second study, the presence of a BRAF mutation in patients with primary stage I-III cutaneous melanomas did not necessarily drive more rapid tumour growth but was associated with poorer melanoma-specific survival in patients with early-stage disease. In the third study, it was found that patients presenting with regional cutaneous metastases have a much better prognosis than those with distant cutaneous metastases. 

Research publications

Our research focuses on understanding primary melanoma, particularly to enhance detection and prevent deaths.

View all Melanoma research publications

Latest news

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Hormones lead to cancer treatment breakthrough article image

Hormones lead to cancer treatment breakthrough

5 Aug 2022

Biological differences between men and women can have an impact on the success of melanoma treatment, according to new research co-led by Alfred oncologist Miles Andrews. 

  • cancer
  • cancer research
  • melanoma
  • research & innovation
Find out more
Helping patients through their melanoma journey article image

Helping patients through their melanoma journey

27 Jul 2022

A new resource provided to patients at the time of their advanced melanoma diagnosis is set to make things easier during what can be an overwhelming time.

  • cancer
  • melanoma
  • patients
Find out more
State-of-the-art melanoma centre to transform cancer care article image

State-of-the-art melanoma centre to transform cancer care

20 Jun 2022

Cancer care for Australians is set to be transformed as building starts on the Paula Fox Melanoma and Cancer Centre at The Alfred.

  • cancer
  • cancer research
  • melanoma
  • research & innovation
Find out more
Head of research
Prof John Kelly Consultant Dermatologist, Victorian Melanoma Service

Victorian Melanoma Service

Victorian Melanoma Service

The Victorian Melanoma Service is one of Australia’s largest multidisciplinary treatment services for melanoma. Our research aims to enhance detection and prevent deaths caused by melanoma.

Find out more about our statewide Victorian Melanoma Service
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