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  • Hypertension research

Hypertension research

Many patients with high blood pressure try to follow a healthy diet, exercise, and take medications — yet their blood pressure is still high.  

A/Prof Walton is coordinating the SPYRAL Hypertension study, a multi-centre, international, randomised, interventional study, using renal denervation.  The purpose of the Trial is to provide information about the safety and efficacy of the investigational Symplicity Spyral™ catheter and the Symplicity G3™ generator to help reduce blood pressure.   To be eligible for the Trial, patients must be between the ages of 20 and 80 and have uncontrolled hypertension, with readings of 150-180/90mmHg.

Current publications

Effect of renal denervation on blood pressure in the presence of antihypertensive drugs: 6-month efficacy and safety results from the SPYRAL HTN-ON MED proof-of-concept randomised trial

View the publication at The Lancet
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A/Prof Antony Walton

Dr Tony Walton is Deputy Director and Head of Catheter Laboratory in the Department of Cardiology.  He is a clinician, interventional cardiologist who specialises in structural heart procedures.

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Profile photo of A/Prof Ingrid Hopper

A/Prof Ingrid Hopper

A/Prof Ingrid Hopper is a heart failure physician and clinical pharmacologist.

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Prof Colin Johnston

Prof Murray Esler

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Latest news

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Getting serious about women’s heart health article image

Getting serious about women’s heart health

18 Aug 2022

Women experiencing chest pain or other symptoms of cardiac distress now have access to a specialist clinic just for them.

  • heart
  • patients
Find out more
Coffee the secret to a long life article image

Coffee the secret to a long life

25 Mar 2022

Drinking coffee could help you live longer according to world-first research by heart specialists at The Alfred.

  • heart
  • research & innovation
Find out more
Keeping hearts alive outside the body article image

Keeping hearts alive outside the body

11 Oct 2021

A ground-breaking trial taking place across Australia and New Zealand could change the future of heart transplantation, potentially enabling up to 15 per cent more heart transplants to occur each year.

  • heart
  • research & innovation
  • transplant
Find out more
Head of research
Prof Murray Esler
Prof Colin Johnston
A/Prof Antony Walton Deputy Director and Head of Catheter Laboratory

Research manager

Bree Davidson

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Participate in clinical trials

Do you want to help us improve the lives of people with heart disease? You could be part of one of our many research trials.  Every volunteer remains confidential and will only be used for the purpose of approved research projects.  You can withdraw at anytime.

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